Japanese scientists manage to eliminate the extra chromosome of Down syndrome

Published at: 05/04/2025 09:28 PM

For the first time in history, Japanese scientists succeeded in removing the extra chromosome that causes Down syndrome in laboratory cells.

The team used the revolutionary CRISPR technique -awarded the Nobel Prize in 2020- to selectively “cut” the extra copy of chromosome 21, responsible for this genetic condition.

Although the breakthrough marks a scientific precedent, researchers emphasize that the application in humans is far from being a reality. “This is preliminary evidence under controlled laboratory conditions,” the experts explained. The study, published recently, only demonstrated effectiveness in isolated cells, not in whole organisms.

The discovery reopens the debate about the limits of genetic engineering. While some celebrate the potential to prevent genetic conditions, others warn of ethical challenges. “Down syndrome is not a disease, but a living condition,” said specialists, while recalling the importance of inclusive policies.

The same method could be investigated for other trisomies associated with serious health complications. However, scientists insist that any clinical application will require years, even decades, of additional research. For now, the greatest value of this finding lies in better understanding the genetic mechanisms behind these conditions.

VTV/Mazo News Team